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Search Results for " ca2 channel "

20

Compounds

Cat No. Product Name Synonyms Targets
T10659 Ca2+ channel agonist 1 Calcium Channel , CDK
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.
T8674 SR33805 Calcium Channel
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)
TN2322 Yangambin Calcium Channel , PAFR
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...
T13047 Synta66 Calcium Channel
Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease.
T6S1418 Praeruptorin C Antioxidant , Calcium Channel
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...
T12015 Methyl homoveratrate Others
Methyl homoveratrate, a McN5691 (RWJ-26240) metabolite detected in vivo in plasma, urine, and fecal extracts, functions as a voltage-sensitive calcium channel blocker.
T7603 Pinaverium bromide Calcium Channel
Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain, diarrhea and intestinal discomfort.
T4294 NS 11021 NS11021 Potassium Channel
NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels
T3102 NS-1619 Apoptosis , Potassium Channel
NS1619 have cardio-protective effects after ischemia-reperfusion injury.
T2519 Lercanidipine Masnidipine Calcium Channel
Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.
T5850 Benzamil Benzamil (hydrochloride) Na+/Ca2+ Exchanger , Sodium Channel
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
T10885 CRAC intermediate 2 Others , Calcium Channel
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis.
T15423 GSK-7975A Calcium Channel
GSK-7975A is a potent and orally available inhibitor of CRAC channel.
T8863 VK-II-36 Others
VK-II-36, a carvedilol analog, suppresses sarcoplasmic reticulum (SR) Ca(2+) release but does not block the β-receptor.
T8787 Drotaverine hydrochloride PDE
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela...
T16873 SERCA2a activator 1 Calcium Channel
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the systolic and diastolic functions of the heart.
T10690 Cav 2.2 blocker 1 Calcium Channel
Cav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain.
T0728 Ethosuximide Zarontin Calcium Channel
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures.
T8206 Cycleanine Others
Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.
T3904 Gomisin J Calcium Channel , AMPK
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK...
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